She has received a B.Sc. with first class honors from the University of Glasgow, a Ph.D. in Viral carcinogenesis at the Medical Research Council Virology Institute in Scotland and completed postdoctoral training at the National Institutes for Cancer Research in Washington DC, US as a prestigious Fogarty Fellow in Molecular Biology. She joined the Ludwig Cancer Institute in 1989 and McGill University in 1991. She was the Associate Director of Fundamental Research for MUHC-RI (2003-6) Director of the Molecular Oncology Group at the McGill University Health Centre (2006-8), Scientific Director of the Institute of Cancer Research for the CIHR (2008-13), co-chair of the Canadian Cancer Research Alliance (2008-2010) and is now Director of the Rosalind and Morris Goodman Cancer Institute (2013-present). She is a recipient of a Canadian Cancer Research Alliance Award (2015) for Exceptional Leadership in Cancer Research, and also a recipient of the Canadian Society for Molecular Biosciences Arthur Wynne Gold Medal Prize (2016) for having made major contributions to biochemistry, molecular and cell biology in Canada.
She was the elected chair of the Tumour Microenvironment Network of the American Association for Cancer Research (2015-2017). Most recently she is a recipient of the Canadian Cancer Society Robert L. Noble Prize for outstanding achievements in basic biomedical cancer research (2017), the Quebec Breast Cancer Foundation Grand Prix Scientifique (2019), and the Club de Recherches Cliniques du Québec Michel Sarrazin Award and the Y Womens Award (2021).
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