Logo Rosalind & Morris Goodman Cancer Institute

2024

Naineni, S. K., Bhatt, G., Jiramongkolsiri, E., Robert, F., Cencic, R., Huang, S., Nagar, B., & Pelletier, J. (2024). Protein-RNA interactions mediated by silvestrol-insight into a unique molecular clamp. Nucleic Acids Res.

Tabaries, S., Robert, A., Marcil, A., Ling, B., Acchione, M., Lippens, J., Page, M., Fortin, A., Meury, L., Coutu, M., Annis, M. G., Girondel, C., Navarre, J., Jaramillo, M., Moraitis, A. N., & Siegel, P. M. (2024). Anti-Claudin-2 Antibody-Drug Conjugates for the Treatment of Colorectal Cancer Liver Metastasis. Mol Cancer Ther, 23(10), 1459-1470.

Valbon, S. F., Lebel, M. E., Feldman, H. A., Condotta, S. A., Dong, M., Giordano, D., Waggoner, S. N., Melichar, H. J., & Richer, M. J. (2024). Type I interferon induced during chronic viral infection favors B-cell development in the thymus. Immunol Cell Biol, 102(9), 801-816.

Yang, Y., Azzuolo, A., Fodil, N., & Gros, P. (2024). Gene: environment interactions in immune and inflammatory responses to severe acute respiratory syndrome coronavirus 2 infection. Curr Opin Immunol, 90, 102459.

Huang, Z., Wiebe, S., Nagpal, A., Choi, J., Walters, C., Mahmood, N., Khoutorsky, A., Lacaille, J. C., & Sonenberg, N. (2024). Dysregulating mTORC1-4E-BP2 signaling in GABAergic interneurons impairs hippocampus-dependent learning and memory. Learn Mem, 31(10-11).

Gu, Y., Taifour, T., Bui, T., Zuo, D., Pacis, A., Poirier, A., Attalla, S., Fortier, A. M., Sanguin-Gendreau, V., Pan, T. C., Papavasiliou, V., Lin, N. U., Hughes, M. E., Smith, K., Park, M., Tremblay, M. L., Chodosh, L. A., Jeselsohn, R., & Muller, W. J. (2024). Osteopontin is a therapeutic target that drives breast cancer recurrence. Nat Commun, 15(1), 9174.

Kammili, A., Trepanier, M., Cools-Lartigue, J., Ferri, L. E., & Mueller, C. L. (2024). Outcomes after revisional surgery for paraesophageal hernias at a high-volume tertiary care center. Surg Endosc.

Nickerson, J. L., Cyr, C., Arseneau, R. J., Lee, S. N., Condon-Oldreive, S., Zogopoulos, G., Roberts, K., Kim, C. A., Ng, S. S. W., Haider, M., Villalba, E., Stephenson, L., Tsang, E., Johnston, B., Gala-Lopez, B., Cooper, V., Hannon, B., Gangloff, A., Gill, S., Servidio-Italiano, F., & Ramjeesingh, R. (2024). Canadian National Pancreas Conference 2023: A Review of Multidisciplinary Engagement in Pancreatic Cancer Care. Curr Oncol, 31(10), 6191-6204.

St-Pierre, J., Coca-Martinez, M., Drummond, K., Minnella, E., Ramanakumar, A. V., Ferri, L., Carli, F., & Scheede-Bergdahl, C. (2024). Multimodal prehabilitation to enhance functional capacity of patients with esophageal cancer during concurrent neoadjuvant chemotherapies-a randomized feasibility trial. Dis Esophagus.

Artusa, P., Nguyen Yamamoto, L., Barbier, C., Valbon, S. F., Aghazadeh Habashi, Y., Djambazian, H., Ismailova, A., Lebel, M. E., Salehi-Tabar, R., Sarmadi, F., Ragoussis, J., Goltzman, D., Melichar, H. J., & White, J. H. (2024). Skewed epithelial cell differentiation and premature aging of the thymus in the absence of vitamin D signaling. Sci Adv, 10(39), eadm9582. 

Sorin, M., Prosty, C., & Spicer, J. D. (2024). Meta-Analysis Methods for Neoadjuvant Chemoimmunotherapy for Non-Small Cell Lung Cancer-Reply. JAMA Oncol

Gao, A. Y. L., Inglebert, Y., Shi, R., Ilie, A., Popic, J., Mustian, J., Sonenberg, N., Orlowski, J., & McKinney, R. A. (2024). Impaired hippocampal plasticity associated with loss of recycling endosomal SLC9A6/NHE6 is ameliorated by the TrkB agonist 7,8-dihydroxyflavone. Biochim Biophys Acta Mol Basis Dis, 167529. 

Thivierge, C., Bellefeuille, M., Diwan, S. S., Dyakov, B. J. A., Leventis, R., Perron, G., Najafabadi, H. S., Gravel, S. P., Gingras, A. C., & Duchaine, T. F. (2024). Paraspeckle-independent co-transcriptional regulation of nuclear microRNA biogenesis by SFPQ. Cell Rep, 43(9), 114695. 

Petrachkova, T., Soldatkina, O., Leduy, L., & Nepveu, A. (2024). The BCL11A transcription factor stimulates the enzymatic activities of the OGG1 DNA glycosylase. Biol Chem

Spicer, J. D., Garassino, M. C., Wakelee, H., Liberman, M., Kato, T., Tsuboi, M., Lee, S. H., Chen, K. N., Dooms, C., Majem, M., Eigendorff, E., Martinengo, G. L., Bylicki, O., Rodriguez-Abreu, D., Chaft, J. E., Novello, S., Yang, J., Arunachalam, A., Keller, S. M., Samkari, A., Gao, S., & Investigators, K.-. (2024). Neoadjuvant pembrolizumab plus chemotherapy followed by adjuvant pembrolizumab compared with neoadjuvant chemotherapy alone in patients with early-stage non-small-cell lung cancer (KEYNOTE-671): a randomised, double-blind, placebo-controlled, phase 3 trial. Lancet, 404(10459), 1240-1252. 

Andrade, A. F., Annett, A., Karimi, E., Topouza, D. G., Rezanejad, M., Liu, Y., McNicholas, M., Gonzalez Santiago, E. G., Llivichuzhca-Loja, D., Gehlhaar, A., Jessa, S., De Cola, A., Chandarana, B., Russo, C., Faury, D., Danieau, G., Puligandla, E., Wei, Y., Zeinieh, M., Wu, Q., Hebert, S., Juretic, N., Nakada, E. M., Krug, B., Larouche, V., Weil, A. G., Dudley, R. W. R., Karamchandani, J., Agnihotri, S., Quail, D. F., Ellezam, B., Konnikova, L., Walsh, L. A., Pathania, M., Kleinman, C. L., & Jabado, N. (2024). Immune landscape of oncohistone-mutant gliomas reveals diverse myeloid populations and tumor-promoting function. Nat Commun, 15(1), 7769. 

Dickinson, K., Sharma, A., Agnihotram, R. V., Altuntur, S., Park, M., Meterissian, S., & Burnier, J. V. (2024). Circulating Tumor DNA and Survival in Metastatic Breast Cancer: A Systematic Review and Meta-Analysis. JAMA Netw Open, 7(9), e2431722. 

Nevo, Y., Tankel, J., Zao, H., Ramirez, J., Cools-Lartigue, J., Muller, C., Alcindor, T., & Ferri, L. (2024). ASO Visual Abstract: Influence of Neoadjuvant Immunotherapy-Chemotherapy on Perioperative Outcomes in Locally Advanced Esophageal Adenocarcinoma. Ann Surg Oncol, 31(9), 5775. 

Keiser, P. T., Zhang, W., Ricca, M., Wacquiez, A., Grimins, A., Cencic, R., Patten, J. J., Shah, P., Padilha, E., Connor, J. H., Pelletier, J., Lyons, S. M., Saeed, M., Brown, L. E., Porco, J. A., Jr., & Davey, R. A. (2024). Amidino-Rocaglates (ADRs), a class of synthetic rocaglates, are potent inhibitors of SARS-CoV-2 replication through inhibition of viral protein synthesis. Antiviral Res, 105976.

Huang, Z., Wiebe, S., Marsal-Garcia, L., Gantois, I., & Sonenberg, N. (2024). Strategies for Assessing Autistic-Like Behaviors in Mice. J Vis Exp(211).

Nandi I, Ji L, Smith HW, Avizonis D, Papavasiliou V, Lavoie C, Pacis A, Attalla S, Sanguin-Gendreau V, Muller WJ. Targeting fatty acid oxidation enhances response to HER2-targeted therapy. Nat Commun. 2024 Aug 3;15(1):6587.


Heath J, Mirabelli C, Annis MG, Sabourin V, Hébert S, Findlay S, Kim H, Witcher M, Kleinman CL, Siegel PM, Orthwein A, Ursini-Siegel J. The Neurodevelopmental Protein POGZ Suppresses Metastasis in Triple Negative Breast Cancer by Attenuating TGFβ Signaling. Cancer Res. 2024 Aug 13. Epub ahead of print.


Jin Y, Cai D, Mo L, Jing G, Zeng L, Cheng H, Guo Q, Dai M, Wang Y, Chen J, Chen G, Li X, Shi S. Multifunctional nanogel loaded with cerium oxide nanozyme and CX3CL1 protein: Targeted immunomodulation and retinal protection in uveitis rat model. Biomaterials. 2024 Sep;309:122617.


Mongeon B, Hébert-Doutreloux J, Surendran A, Karimi E, Fiset B, Quail DF, Walsh LA, Jenner AL, Craig M. Spatial computational modelling illuminates the role of the tumour microenvironment for treating glioblastoma with immunotherapies. NPJ Syst Biol Appl. 2024 Aug 18;10(1):91.


Ribeiro FC, Cozachenco D, Argyrousi EK, Staniszewski A, Wiebe S, Calixtro JD, Soares-Neto R, Al-Chami A, Sayegh FE, Bermudez S, Arsenault E, Cossenza M, Lacaille JC, Nader K, Sun H, De Felice FG, Lourenco MV, Arancio O, Aguilar-Valles A, Sonenberg N, Ferreira ST. The ketamine metabolite (2R,6R)-hydroxynorketamine rescues hippocampal mRNA translation, synaptic plasticity and memory in mouse models of Alzheimer's disease. Alzheimers Dement. 2024 Aug;20(8):5398-5410.


Walker NM, Ibuki Y, McLinden AP, Misumi K, Mitchell DC, Kleer GG, Lock AM, Vittal R, Sonenberg N, Garner AL, Lama VN. MNK-driven eIF4E phosphorylation regulates the fibrogenic transformation of mesenchymal cells and chronic lung allograft dysfunction. J Clin Invest. 2024 Aug 15;134(16):e168393.


Wang P, Li Z, Kim SH, Xu H, Huang H, Yang C, Snape A, Choi JH, Bermudez S, Boivin MN, Ferry N, Karamchandani J, Nagar B, Sonenberg N. PPM1G dephosphorylates eIF4E in control of mRNA translation and cell proliferation. Life Sci Alliance. 2024 Aug 7;7(10):e202402755.


Wang Z, Thakare RP, Chitale S, Mishra AK, Goldstein SI, Fan AC, Li R, Zhu LJ, Brown LE, Cencic R, Huang S, Green MR, Pelletier J, Malonia SK, Porco JA Jr. Identification of Rocaglate Acyl Sulfamides as Selective Inhibitors of Glioblastoma Stem Cells. ACS Cent Sci. 2024 Aug 8;10(8):1640-1656.


Wei C, Fu D, Ma T, Chen M, Wang F, Chen G, Wang Z. Sensing patches for biomarker identification in skin-derived biofluids. Biosens Bioelectron. 2024 Aug 15;258:116326.

 

Keiser, P. T., Zhang, W., Ricca, M., Wacquiez, A., Grimins, A., Cencic, R., Patten, J. J., Shah, P., Padilha, E., Connor, J. H., Pelletier, J., Lyons, S. M., Saeed, M., Brown, L. E., Porco, J. A., Jr., & Davey, R. A. (2024). Amidino-Rocaglates (ADRs), a class of synthetic rocaglates, are potent inhibitors of SARS-CoV-2 replication through inhibition of viral protein synthesis. Antiviral Res, 105976. 

Choi, J. H., Marsal-Garcia, L., Peraldi, E., Walters, C., Huang, Z., Gantois, I., & Sonenberg, N. (2024). Early metformin treatment: An effective approach for targeting fragile X syndrome pathophysiology. Proc Natl Acad Sci U S A, 121(31), e2407546121. 

Gallina, F. T., Balzano, V., Porciello, N., Taje, R., Forcella, D., Melis, E., Letizia Cecere, F., Fusco, F., Buglioni, S., Visca, P., Nistico, P., Cappuzzo, F., & Spicer, J. (2024). Trajectory of PD-L1 expression in a patient underwent neoadjuvant chemo-immunotherapy for resectable NSCLC. Lung Cancer, 194, 107900. 

Mahmood, N., Choi, J. H., Wu, P. Y., Dooling, S. W., Watkins, T. A., Huang, Z., Lipman, J., Zhao, H., Yang, A., Silversmith, J., Inglebert, Y., Koumenis, C., Sharma, V., Lacaille, J. C., Sossin, W. S., Khoutorsky, A., McKinney, R. A., Costa-Mattioli, M., & Sonenberg, N. (2024). The ISR downstream target ATF4 represses long-term memory in a cell type-specific manner. Proc Natl Acad Sci U S A, 121(31), e2407472121. 

Biondini, M., Lehuede, C., Tabaries, S., Annis, M. G., Pacis, A., Ma, E. H., Tam, C., Hsu, B. E., Audet-Delage, Y., Abu-Thuraia, A., Girondel, C., Sabourin, V., Totten, S. P., de Sa Tavares Russo, M., Bridon, G., Avizonis, D., Guiot, M. C., St-Pierre, J., Ursini-Siegel, J., Jones, R., & Siegel, P. M. (2024). Metastatic breast cancer cells are metabolically reprogrammed to maintain redox homeostasis during metastasis. Redox Biol, 75, 103276. 

Choi, J. H., Luo, J., Hesketh, G. G., Guo, S., Pistofidis, A., Ladak, R. J., An, Y., Naeli, P., Alain, T., Schmeing, T. M., Gingras, A. C., Duchaine, T., Zhang, X., Sonenberg, N., & Jafarnejad, S. M. (2024). Repression of mRNA translation initiation by GIGYF1 via disrupting the eIF3-eIF4G1 interaction. Sci Adv, 10(29), eadl5638. 

Cai, Z., Zhong, Q., Feng, Y., Wang, Q., Zhang, Z., Wei, C., Yin, Z., Liang, C., Liew, C. W., Kazak, L., Cypess, A. M., Liu, Z., & Cai, K. (2024). Non-invasive mapping of brown adipose tissue activity with magnetic resonance imaging. Nat Metab, 6(7), 1367-1379. 

Tripathi, M., Gauthier, K., Sandireddy, R., Zhou, J., Guptta, P., Sakthivel, S., Teo, W. W., Naing, Y. T., Arul, K., Tikno, K., Park, S. H., Wu, Y., Wang, L., Bay, B. H., Sun, L., Giguere, V., Chow, P. K. H., Ghosh, S., McDonnell, D. P., Yen, P. M., & Singh, B. K. (2024). Esrra regulates Rplp1-mediated translation of lysosome proteins suppressed in metabolic dysfunction-associated steatohepatitis and reversed by alternate day fasting. Mol Metab, 101997. 

Girard, N., Besada, M., Rogula, B., Lucherini, S., Vo, L., Chaudhary, M. A., Goring, S., Lozano-Ortega, G., Tran, M., Varol, N., Waser, N., Lee, J. M., & Spicer, J. (2024). Comparative Efficacy of Neoadjuvant Nivolumab Plus Chemotherapy versus Conventional Comparator Treatments in Resectable Non-Small-Cell Lung Cancer: A Systematic Literature Review and Network Meta-Analysis. Cancers (Basel), 16(13). 

Huang, Y. H., Yoon, C. H., Gandhi, A., Hanley, T., Castrillon, C., Kondo, Y., Lin, X., Kim, W., Yang, C., Driouchi, A., Carroll, M., Gray-Owen, S. D., Wesemann, D. R., Drake, C. G., Bertagnolli, M. M., Beauchemin, N., & Blumberg, R. S. (2024). High-dimensional mapping of human CEACAM1 expression on immune cells and association with melanoma drug resistance. Commun Med (Lond), 4(1), 128. 

Sepesi, B., Mehran, R., Spicer, J., & Cascone, T. (2024). NEOSTAR trial and the current status of neoadjuvant therapy in non-small cell lung cancer. J Thorac Cardiovasc Surg, 167(6), 1936-1942.

Poirier, A., Picard, C., Labonte, A., Aubry, I., Auld, D., Zetterberg, H., Blennow, K., group, P.-A. r., Tremblay, M. L., & Poirier, J. (2024). PTPRS is a novel marker for early Tau pathology and synaptic integrity in Alzheimer's disease. Sci Rep, 14(1), 14718.

Markar, S. R., Sgromo, B., Evans, R., Griffiths, E. A., Alfieri, R., Castoro, C., Gronnier, C., Gutschow, C. A., Piessen, G., Capovilla, G., Grimminger, P. P., Low, D. E., Gossage, J., Gisbertz, S. S., Ruurda, J., van Hillegersberg, R., D'Journo X, B., Phillips, A. W., Rosati, R., Hanna, G. B., Maynard, N., Hofstetter, W., Ferri, L., Berge Henegouwen, M. I., & Owen, R. (2024). The Prognostic Impact of Minimally Invasive Esophagectomy on Survival after Esophagectomy following a Delayed Interval after Chemoradiotherapy; A Secondary Analysis of the DICE Study. Ann Surg.

Martinez, S., Wu, S., Geuenich, M., Malik, A., Weber, R., Woo, T., Zhang, A., Jang, G. H., Dervovic, D., Al-Zahrani, K. N., Tsai, R., Fodil, N., Gros, P., Gallinger, S., Neely, G. G., Notta, F., Sendoel, A., Campbell, K., Elling, U., & Schramek, D. (2024). In vivo CRISPR screens reveal SCAF1 and USP15 as drivers of pancreatic cancer. Nat Commun, 15(1), 5266.

Spicer, J. D., Cascone, T., Wynes, M. W., Ahn, M. J., Dacic, S., Felip, E., Forde, P. M., Higgins, K. A., Kris, M. G., Mitsudomi, T., Provencio, M., Senan, S., Solomon, B. J., Tsao, M. S., Tsuboi, M., Wakelee, H. A., Wu, Y. L., Chih-Hsin Yang, J., Zhou, C., Harpole, D. H., & Kelly, K. L. (2024). Neoadjuvant and Adjuvant Treatment for Early-Stage Resectable Non-small Cell Lung Cancer (NSCLC): Consensus Recommendations from the International Association for the Study of Lung Cancer (IASLC). J Thorac Oncol.

Digby, G. C., Lam, S., Tammemagi, M. C., Finley, C., Dennie, C., Snow, S., Habert, J., Taylor, J., Gonzalez, A. V., Spicer, J., Sahota, J., Guy, D., Marino, P., & Manos, D. (2024). Recommendations to Improve Management of Incidental Pulmonary Nodules in Canada: Expert Panel Consensus. Can Assoc Radiol J, 8465371241257910.

Tankel, J., Nevo, Y., Al Shehhi, R., Sakalla, R., Dehghani, M., Spicer, J., Najmeh, S., Mueller, C., Ferri, L., & Cools-Lartigue, J. (2024). Impact of bulky loco-regional lymphadenopathy in esophageal adenocarcinoma on survival: a retrospective single center analysis. Dis Esophagus.

Cagnetta, R., Lacaille, J. C., & Sonenberg, N. (2024). Exploration of new space elicits phosphorylation of GluA1(Ser831) and S6K and expression of Arc in the hippocampus in vivo as in long-term potentiation. Mol Brain, 17(1), 35.

Khalil, A. A., Smits, D., Haughton, P. D., Koorman, T., Jansen, K. A., Verhagen, M. P., van der Net, M., van Zwieten, K., Enserink, L., Jansen, L., El-Gammal, A. G., Visser, D., Pasolli, M., Tak, M., Westland, D., van Diest, P. J., Moelans, C. B., Roukens, M. G., Tavares, S., Fortier, A. M., Park, M., Fodde, R., Gloerich, M., Zwartkruis, F. J. T., Derksen, P. W., & de Rooij, J. (2024). A YAP-centered mechanotransduction loop drives collective breast cancer cell invasion. Nat Commun, 15(1), 4866.

Kumar, A., Laborit Labrada, B., Lavallee-Bourget, M. H., Forest, M. P., Schwab, M., Bellmann, K., Houde, V., Beauchemin, N., Laplante, M., & Marette, A. (2024). Regulation of PPARgamma2 Stability and Activity by SHP-1. Mol Cell Biol, 1-12.

Scholtes, C., Dufour, C. R., Pleynet, E., Kamyabiazar, S., Hutton, P., Baby, R., Guluzian, C., & Giguere, V. (2024). Identification of a chromatin-bound ERRalpha interactome network in mouse liver. Mol Metab, 83, 101925.

Raghuram, N., Temel, E. I., Kawamata, T., Kozma, K. J., Loch, A. J., Wang, W., Adams, J. R., Muller, W. J., & Egan, S. E. (2024). Elevated expression of wildtype RhoC promotes ErbB2- and Pik3ca-induced mammary tumor formation. Breast Cancer Res, 26(1), 86.

Tankel, J., Sticca, G., Kammili, A., Dehghani, M., Sakalla, R., Ahmed, N., Meng, A., Najmeh, S., Spicer, J., Cools-Lartigue, J., Ferri, L., & Mueller, C. (2024). ERAS following Gastrectomy for Octo- and Nonagenarians: A Single-Center Retrospective Analysis. J Laparoendosc Adv Surg Tech A.

Cascone, T., Awad, M. M., Spicer, J. D., He, J., Lu, S., Sepesi, B., Tanaka, F., Taube, J. M., Cornelissen, R., Havel, L., Karaseva, N., Kuzdzal, J., Petruzelka, L. B., Wu, L., Pujol, J. L., Ito, H., Ciuleanu, T. E., de Oliveira Muniz Koch, L., Janssens, A., Alexandru, A., Bohnet, S., Moiseyenko, F. V., Gao, Y., Watanabe, Y., Coronado Erdmann, C., Sathyanarayana, P., Meadows-Shropshire, S., Blum, S. I., Provencio Pulla, M., & CheckMate, T. I. (2024). Perioperative Nivolumab in Resectable Lung Cancer. N Engl J Med, 390(19), 1756-1769.

Gnanapragasam, A., Kirbizakis, E., Li, A., White, K. H., Mortenson, K. L., Cavalcante de Moura, J., Jawhar, W., Yan, Y., Falter, R., Russett, C., Giannias, B., Camilleri-Broet, S., Bertos, N., Cools-Lartigue, J., Garzia, L., Sangwan, V., Ferri, L. E., Zhang, X., & Bailey, S. D. (2024). HiChIP-based Epigenomic Footprinting Identifies a Promoter Variant of UXS1 that Confers Genetic Susceptibility to Gastroesophageal Cancer. Cancer Res.

Dore, S., Ali, M., Sorin, M., McDowell, S. A. C., Desharnais, L., Breton, V., Yu, M. W., Arabzadeh, A., Ryan, M. I., Milette, S., Quail, D. F., & Walsh, L. A. (2024). Exploring the prognostic significance of arm-level copy number alterations in triple-negative breast cancer. Oncogene.

Agrawal, S., Buyan, A., Severin, J., Koido, M., Alam, T., Abugessaisa, I., Chang, H. Y., Dostie, J., Itoh, M., Kere, J., Kondo, N., Li, Y., Makeev, V. J., Mendez, M., Okazaki, Y., Ramilowski, J. A., Sigorskikh, A. I., Strug, L. J., Yagi, K., Yasuzawa, K., Yip, C. W., Hon, C. C., Hoffman, M. M., Terao, C., Kulakovskiy, I. V., Kasukawa, T., Shin, J. W., Carninci, P., & de Hoon, M. J. L. (2024). Annotation of nuclear lncRNAs based on chromatin interactions. PLoS One, 19(5), e0295971.

Huang, F., Goncalves, C., Bartish, M., Remy-Sarrazin, J., Issa, M. E., Cordeiro, B., Guo, Q., Emond, A., Attias, M., Yang, W., Plourde, D., Su, J., Gimeno, M. G., Zhan, Y., Galan, A., Rzymski, T., Mazan, M., Masiejczyk, M., Faber, J., Khoury, E., Benoit, A., Gagnon, N., Dankort, D., Journe, F., Ghanem, G. E., Krawczyk, C. M., Saragovi, H. U., Piccirillo, C. A., Sonenberg, N., Topisirovic, I., Rudd, C. E., Miller, W. H., Jr., & Del Rincon, S. V. (2024). Inhibiting the MNK1/2-eIF4E axis impairs melanoma phenotype switching and potentiates antitumor immune responses. J Clin Invest, 134(9).

Pilon, Y., Rokah, M., Seitlinger, J., Sepesi, B., Rayes, R. F., Cools-Lartigue, J., Najmeh, S., Sirois, C., Mulder, D., Ferri, L., Abdulkarim, B., Ezer, N., Fraser, R., Camilleri-Broet, S., Fiset, P. O., Wong, A., Sud, S., Langleben, A., Agulnik, J., Pepe, C., Shieh, B., Hirsh, V., Ofiara, L., Owen, S., & Spicer, J. D. (2024). Transitioning to Neoadjuvant Therapy for Resectable Non-Small Cell Lung Cancer: Trends and Surgical Outcomes in a Regionalized Pulmonary Oncology Network. Clin Lung Cancer, 25(3), e133-e144 e134.

Alcolea, M. P., Alonso-Curbelo, D., Ambrogio, C., Bullman, S., Correia, A. L., Ernst, A., Halbrook, C. J., Kelly, G. L., Lund, A. W., Quail, D. F., Ruscetti, M., Shema, E., Stromnes, I. M., & Tam, W. L. (2024). Cancer Hallmarks: Piecing the Puzzle Together. Cancer Discov, 14(4), 674-682.

Tankel, J., Sakalla, R., Boukhili, N., Dehghani, M., Spicer, J., Najmeh, S., Cools-Lartigue, J., Asselah, J., Soldera, S., Alcindor, T., Alfieri, J., David, M., Mueller, C., & Ferri, L. (2024). Survival in esophageal cancer with non-regional lymphadenopathy: A propensity score matched analysis. J Gastrointest Surg.

Messing, M., Gatti, D. M., Mashhouri, S., Nantel, S., Sultana, S., Westhaver, L. P., Patel, K. D., Marshall, A. J., Haeryfar, S. M. M., Jenne, C. N., Abraham, N., Melichar, H. J., McNagny, K. M., & Valdez Tejeira, Y. (2024). A Retrospective Analysis of Leadership, Awardees, and Member Gender Representation of the Canadian Society for Immunology. J Immunol, 212(8), 1257-1267.

Spinelli, C., Adnani, L., Meehan, B., Montermini, L., Huang, S., Kim, M., Nishimura, T., Croul, S. E., Nakano, I., Riazalhosseini, Y., & Rak, J. (2024). Mesenchymal glioma stem cells trigger vasectasia-distinct neovascularization process stimulated by extracellular vesicles carrying EGFR. Nat Commun, 15(1), 2865.

Tankel, J., Patel, D., Nevo, Y., Najmeh, S., Spicer, J., Mulder, D., Mueller, C., Ferri, L., & Cools-Lartigue, J. (2023). ASO Visual Abstract: Postoperative Outcomes and Quality of Life After Left Thoracoabdominal Esophagogastrectomy-Contrasting Esophagogastrostomy with Esophagojejunostomy. Ann Surg Oncol, 30(13), 8278-8279.

Perez-Quintero, L. A., Abidin, B. M., & Tremblay, M. L. (2024). Immunotherapeutic implications of negative regulation by protein tyrosine phosphatases in T cells: the emerging cases of PTP1B and TCPTP. Front Med (Lausanne), 11, 1364778.

Cao, X., Fang, T., Chen, M., Ning, T., Li, J., Siegel, P. M., Park, M., Chen, Z., & Chen, G. (2024). Trehalose enhanced cold atmospheric plasma-mediated cancer treatment. Biomaterials, 309, 122582.

Zhu, X., Fu, Z., Dutchak, K., Arabzadeh, A., Milette, S., Steinberger, J., Morin, G., Monast, A., Pilon, V., Kong, T., Adams, B. N., Prando Munhoz, E., Hosein, H. J. B., Fang, T., Su, J., Xue, Y., Rayes, R., Sangwan, V., Walsh, L. A., Chen, G., Quail, D. F., Spicer, J. D., Park, M., Dankort, D., & Huang, S. (2024). Cotargeting CDK4/6 and BRD4 Promotes Senescence and Ferroptosis Sensitivity in Cancer. Cancer Res, 84(8), 1333-1351.

Shahzad, M. H., Spicer, J. D., Rusch, V. W., & Kneuertz, P. J. (2024). Perioperative Immunotherapy for Node-Negative Non-Small Cell Lung Cancer - Current Evidence and Future Directions. Ann Thorac Surg.

Zogopoulos, G., Haimi, I., Sanoba, S. A., Everett, J. N., Wang, Y., Katona, B. W., Farrell, J. J., Grossberg, A. J., Paiella, S., Klute, K. A., Bi, Y., Wallace, M. B., Kwon, R. S., Stoffel, E. M., Wadlow, R. C., Sussman, D. A., Merchant, N. B., Permuth, J. B., Golan, T., Raitses-Gurevich, M., Lowy, A. M., Liau, J., Jeter, J. M., Lindberg, J. M., Chung, D. C., Earl, J., Brentnall, T. A., Schrader, K. A., Kaul, V., Huang, C., Chandarana, H., Smerdon, C., Graff, J. J., Kastrinos, F., Kupfer, S. S., Lucas, A. L., Sears, R. C., Brand, R. E., Parmigiani, G., Simeone, D. M., & Consortium, P. (2024). The Pancreatic Cancer Early Detection (PRECEDE) Study is a Global Effort to Drive Early Detection: Baseline Imaging Findings in High-Risk Individuals. J Natl Compr Canc Netw, 22(3), 158-166.

Alcolea, M. P., Alonso-Curbelo, D., Ambrogio, C., Bullman, S., Correia, A. L., Ernst, A., Halbrook, C. J., Kelly, G. L., Lund, A. W., Quail, D. F., Ruscetti, M., Shema, E., Stromnes, I. M., & Tam, W. L. (2024). Cancer Hallmarks: Piecing the Puzzle Together. Cancer Discov, 14(4), 674-682.

Kuzmin, E., Baker, T. M., Lesluyes, T., Monlong, J., Abe, K. T., Coelho, P. P., Schwartz, M., Del Corpo, J., Zou, D., Morin, G., Pacis, A., Yang, Y., Martinez, C., Barber, J., Kuasne, H., Li, R., Bourgey, M., Fortier, A. M., Davison, P. G., Omeroglu, A., Guiot, M. C., Morris, Q., Kleinman, C. L., Huang, S., Gingras, A. C., Ragoussis, J., Bourque, G., Van Loo, P., & Park, M. (2024). Evolution of chromosome-arm aberrations in breast cancer through genetic network rewiring. Cell Rep, 43(4), 113988

Gottig, L., Jummer, S., Staehler, L., Groitl, P., Karimi, M., Blanchette, P., Kosulin, K., Branton, P. E., & Schreiner, S. (2024). The human adenovirus PI3K-Akt activator E4orf1 is targeted by the tumor suppressor p53. J Virol, e0170123.

Kim, H., Lebeau, B., Papadopoli, D., Jovanovic, P., Russo, M., Avizonis, D., Morita, M., Afzali, F., Ursini-Siegel, J., Postovit, L. M., Witcher, M., & Topisirovic, I. (2024). MTOR modulation induces selective perturbations in histone methylation which influence the anti-proliferative effects of mTOR inhibitors. iScience, 27(3), 109188.

Chen, Y., MacIsaac, S., Young, M., Ahodakin, M., Jeagal, L. W., Boucher, M., Agulnik, J., Boulanger, N., Camilleri-Broet, S., Ezer, N., Gonzalez, A. V., Owen, S., Pepe, C., Spicer, J., Wang, H., White-Dupuis, S., Watt, L., Grey, M., Benedetti, A., & Khan, F. A. (2024). Nunavimmi puvakkut kaggutimik aanniaqarniq: Qanuilirqitaa? Lung cancer in Nunavik: How are we doing? A retrospective matched cohort study. CMAJ, 196(6), E177-E186.

Lorange, J. P., Katz, A., Tankel, J., Huynh, C., & Spicer, J. (2024). Comparing immediate postoperative outcomes of different VATS approaches for anatomical lung resection: a single-centre retrospective study. Can J Surg, 67(2), E142-E148.

Nevo, Y., Tankel, J., Zhao, H., Ramirez, J., Cools-Lartigue, J., Muller, C., Alcindor, T., & Ferri, L. (2024). Influence of Neoadjuvant Immunotherapy-Chemotherapy on Perioperative Outcomes in Locally Advanced Esophageal Adenocarcinoma. Ann Surg Oncol.

Sorin, M., Prosty, C., Ghaleb, L., Nie, K., Katergi, K., Shahzad, M. H., Dube, L. R., Atallah, A., Swaby, A., Dankner, M., Crump, T., Walsh, L. A., Fiset, P. O., Sepesi, B., Forde, P. M., Cascone, T., Provencio, M., & Spicer, J. D. (2024). Neoadjuvant Chemoimmunotherapy for NSCLC: A Systematic Review and Meta-Analysis. JAMA Oncol.

Blackler, G., Lai-Zhao, Y., Klapak, J., Philpott, H. T., Pitchers, K. K., Maher, A. R., Fiset, B., Walsh, L. A., Gillies, E. R., & Appleton, C. T. (2024). Targeting STAT6-mediated synovial macrophage activation improves pain in experimental knee osteoarthritis. Arthritis Res Ther, 26(1), 73.

Sharma, R., Kalot, R., Levin, Y., Babayeva, S., Kachurina, N., Chung, C. F., Liu, K. J., Bouchard, M., & Torban, E. (2024). The CPLANE protein Fuzzy regulates ciliogenesis by suppressing actin polymerization at the base of the primary cilium via p190A RhoGAP. Development, 151(6).

Gagnon, B., Murphy, J., Simonyan, D., Penafuerte, C. A., Sirois, J., Chasen, M., & Tremblay, M. L. (2024). Cancer anorexia-cachexia syndrome is characterized by more than one inflammatory pathway. J Cachexia Sarcopenia Muscle.

Chen, Y., Han, L., Dufour, C. R., Alfonso, A., & Giguere, V. (2023). Canonical and nuclear mTOR specify distinct transcriptional programs in androgen-dependent prostate cancer cells. Mol Cancer Res. 

Tankel, J., Kammili, A., Meng, A., Dehghani, M., Sakalla, R., Spicer, J., Najmeh, S., Cools-Lartigue, J., Ferri, L., & Mueller, C. (2024). Enhanced recovery after surgery after radical gastrectomy: Improved compliance over time is associated with a shorter postoperative hospital stay. World J Surg, 48(2), 261-270.

Dunne, E. G., Fick, C. N., Isbell, J. M., Chaft, J. E., Altorki, N., Park, B. J., Spicer, J., Forde, P. M., Gomez, D., Iyengar, P., Harpole, D. H., Jr., Stinchcombe, T. E., Liberman, M., Bott, M. J., Adusumilli, P. S., Huang, J., Rocco, G., & Jones, D. R. (2024). The Emerging Role of Immunotherapy in Resectable Non-Small Cell Lung Cancer. Ann Thorac Surg.

Mony, S., Hu, B., Joseph, A., Aihara, H., Ferri, L., Bhatt, A., Mehta, A., Ting, P. S., Chen, A., Kalra, A., Farha, J., Onimaru, M., He, L., Luo, Q., Wang, A. Y., Inoue, H., & Ngamruengphong, S. (2024). Clinical outcomes of endoscopic submucosal dissection for superficial esophageal neoplasia in close proximity to esophageal varices: a multicenter international experience. Endoscopy, 56(2), 119-124.

Vonniessen, B., Tabaries, S., & Siegel, P. M. (2024). Antibody-mediated targeting of Claudins in cancer. Front Oncol, 14, 1320766.

Tankel, J., Safieddine, N., Malthaner, R., French, D., Johnston, B., Finley, C., Darling, G., Ferri, L., Seely, A., & Gowing, S. (2024). A trans-Canadian positive deviance seminar for paraesophageal hernia surgery: Reporting national postoperative outcomes and consensus recommendations. World J Surg.

 

 

Zhu, X., Fu, Z., Dutchak, K., Arabzadeh, A., Milette, S., Steinberger, J., Morin, G., Monast, A., Pilon, V., Kong, T., Adams, B. N., Prando Munhoz, E., Hosein, H. J., Fang, T., Su, J., Xue, Y., Rayes, R., Sangwan, V., Walsh, L. A., Chen, G., Quail, D. F., Spicer, J. D., Park, M., Dankort, D., & Huang, S. (2024). Co-targeting CDK4/6 and BRD4 promotes senescence and ferroptosis sensitivity in cancer. Cancer Res.  

Dankner, M., Maritan, S. M., Priego, N., Kruck, G., Nkili-Meyong, A., Nadaf, J., Zhuang, R., Annis, M. G., Zuo, D., Nowakowski, A., Biondini, M., Kiepas, A., Mourcos, C., Le, P., Charron, F., Inglebert, Y., Savage, P., Theret, L., Guiot, M. C., McKinney, R. A., Muller, W. J., Park, M., Valiente, M., Petrecca, K., & Siegel, P. M. (2024). Invasive growth of brain metastases is linked to CHI3L1 release from pSTAT3-positive astrocytes. Neuro Oncol.  
 
Conchas, G. A. G., O'Kane, G. M., Denroche, R. E., Jang, G. H., Fischer, S., Dodd, A., Picardo, S. L., Holter, S., Wilson, W., Zogopoulos, G., Elimova, E., Prince, R. M., Jang, R. W-J., Moore, M. J., Biagi, J. J., Notta, F., Grant, R. C., Gallinger, S., Tsang, E. S., Knox, J. J. (2024). Characterizing the genomic landscape of locally advanced pancreatic cancer. JCO.    

Rahbani, J. F., Bunk, J., Lagarde, D., Samborska, B., Roesler, A., Xiao, H., Shaw, A., Kaiser, Z., Braun, J. L., Geromella, M. S., Fajardo, V. A., Koza, R. A., & Kazak, L. (2024). Parallel control of cold-triggered adipocyte thermogenesis by UCP1 and CKB. Cell Metab.  

Vickridge, E., Faraco, C. C. F., Lo, F., Rahimian, H., Liu, Z. Y., Tehrani, P. S., Djerir, B., Ramdzan, Z. M., Leduy, L., Marechal, A., Gingras, A. C., & Nepveu, A. (2023). The function of BCL11B in base excision repair contributes to its dual role as an oncogene and a haplo-insufficient tumor suppressor gene. Nucleic Acids Res.  

Cencic, R., Im, Y. K., Naineni, S. K., Moustafa-Kamal, M., Jovanovic, P., Sabourin, V., Annis, M. G., Robert, F., Schmeing, T. M., Koromilas, A., Paquet, M., Teodoro, J. G., Huang, S., Siegel, P. M., Topisirovic, I., Ursini-Siegel, J., & Pelletier, J. (2024). A second-generation eIF4A RNA helicase inhibitor exploits translational reprogramming as a vulnerability in triple-negative breast cancer. Proc Natl Acad Sci U S A, 121(4), e2318093121.  

Magrill, J., Moldoveanu, D., Gu, J., Lajoie, M., & Watson, I. R. (2024). Mapping the single cell spatial immune landscapes of the melanoma microenvironment. Clin Exp Metastasis.  

Ziegler, D. V., Czarnecka-Herok, J., Vernier, M., Scholtes, C., Camprubi, C., Huna, A., Massemin, A., Griveau, A., Machon, C., Guitton, J., Rieusset, J., Vigneron, A. M., Giguere, V., Martin, N., & Bernard, D. (2024). Cholesterol biosynthetic pathway induces cellular senescence through ERRalpha. NPJ Aging, 10(1), 5.

Olivier, J. F., Langlais, D., Jeyakumar, T., Polyak, M. J., Galarneau, L., Cayrol, R., Jiang, H., Molloy, K. R., Xu, G., Suzuki, H., LaCava, J., Gros, P., & Fodil, N. (2024). CCDC88B interacts with RASAL3 and ARHGEF2 and regulates dendritic cell function in neuroinflammation and colitis. Commun Biol, 7(1), 77.  

Lewis, K., La Selva, R., Maldonado, E., Annis, M. G., Najyb, O., Cepeda Canedo, E., Totten, S., Hebert, S., Sabourin, V., Mirabelli, C., Ciccolini, E., Lehuede, C., Choiniere, L., Russo, M., Avizonis, D., Park, M., St-Pierre, J., Kleinman, C. L., Siegel, P. M., & Ursini-Siegel, J. (2024). p66ShcA promotes malignant breast cancer phenotypes by alleviating energetic and oxidative stress. Redox Biol, 70, 103028.  

Poirier, A., Ormode, J. V. S., Aubry, I., Abidin, B. M., Feng, C. H., Martinez-Cordova, Z., Hincapie, A. M., Wu, C., Perez-Quintero, L. A., Wang, C. L., Gingras, A. C., Madrenas, J., & Tremblay, M. L. (2024). The induction of SHP-1 degradation by TAOK3 ensures the responsiveness of T cells to TCR stimulation. Sci Signal, 17(817), eadg4422.

Amiri, M., Kiniry, S. J., Possemato, A. P., Mahmood, N., Basiri, T., Dufour, C. R., Tabatabaei, N., Deng, Q., Bellucci, M. A., Harwalkar, K., Stokes, M. P., Giguere, V., Kaufman, R. J., Yamanaka, Y., Baranov, P. V., Tahmasebi, S., & Sonenberg, N. (2023). Impact of eIF2alpha phosphorylation on the translational landscape of mouse embryonic stem cells. Cell Rep, 43(1), 113615.  

2023

Tankel, J., Spicer, J., Chu, Q., Fiset, P. O., Kidane, B., Leighl, N. B., Joubert, P., Maziak, D., Palma, D., McGuire, A., Melosky, B., Snow, S., Bahig, H., & Blais, N. (2023). Canadian Consensus Recommendations for the Management of Operable Stage II/III Non-Small-Cell Lung Cancer: Results of a Modified Delphi Process. Curr Oncol, 30(12), 10363-10384.  

Qurat Ul, A., Frei, N. F., Khoshiwal, A. M., Stougie, P., Odze, R., Camilleri-Broet, S., Ferri, L., Duits, L. C., Bergman, J., & Stachler, M. D. (2023). Feasibility Study Utilizing NanoString's Digital Spatial Profiling (DSP) Technology for Characterizing the Immune Microenvironment in Barrett's Esophagus Formalin-Fixed Paraffin-Embedded Tissues. Cancers (Basel), 15(24).  

Jones, D., Gingrich, M., Anstee, C., Najmeh, S., Safieddine, N., Darling, G., Malthaner, R., Finley, C., French, D. G., Ferri, L., & Seely, A. (2023). Multicentre positive deviance seminar to generate best practice recommendations to reduce anastomotic leak and length of stay for patients undergoing oesophagectomy. BMJ Open Qual, 12(4).  

Tankel, J., Ijner, T., Ferri, C., Trottenberg, T., Dehghani, M., Najmeh, S., Fiset, P. O., Alsaddah, S., Cools-Lartigue, J., Spicer, J., Mueller, C., & Ferri, L. (2023). Esophagectomy versus observation following endoscopic submucosal dissection of pT1b esophageal adenocarcinoma. Surg Endosc.

Tankel, J., Ahmed, N., Mueller, C., Najmeh, S., Spicer, J., Mulder, D., Cool-Lartigue, J., Rousseau, M., Frechette, D., Sud, S., Kavan, P., Moghrabi, A., Champagne, M., Lemay, F., Dalfen, R., Sirhan, S., Asselah, J., Alcindor, T., & Ferri, L. (2023). Docetaxel-Based Neoadjuvant Chemotherapy Followed by En Bloc Resection for Esophageal Adenocarcinoma: A 15-Year Retrospective Analysis from a Regional Upper Gastrointestinal Cancer Network. Ann Surg Oncol.

Ketel, M. H. M., Klarenbeek, B. R., Eddahchouri, Y., Cheong, E., Cuesta, M. A., van Daele, E., Ferri, L. E., Gisbertz, S. S., Gutschow, C. A., Hubka, M., Holscher, A. H., Law, S., Luyer, M. D. P., Merritt, R. E., Morse, C. R., Mueller, C. L., Nieuwenhuijzen, G. A. P., Nilsson, M., Pattyn, P., Shen, Y., van den Wildenberg, F. J. H., Abma, I. L., Rosman, C., & van Workum, F. (2023). A Video-Based Procedure-Specific Competency Assessment Tool for Minimally Invasive Esophagectomy. JAMA Surg.  

Liu, B., Liu, J. N., Chen, G. J., Xu, C., & Bu, L. L. (2023). Editorial: Cuproptosis and tumor. Front Cell Dev Biol, 11, 1307501. https://doi.org/10.3389/fcell.2023.1307501
Varrone, M., Tavernari, D., Santamaria-Martinez, A., Walsh, L. A., & Ciriello, G. (2024). CellCharter reveals spatial cell niches associated with tissue remodeling and cell plasticity. Nat Genet, 56(1), 74-84
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Hernandez, G., Garcia, A., Weingarten-Gabbay, S., Mishra, R. K., Hussain, T., Amiri, M., Moreno-Hagelsieb, G., Montiel-Davalos, A., Lasko, P., & Sonenberg, N. (2023). Functional analysis of the AUG initiator codon context reveals novel conserved sequences that disfavor mRNA translation in eukaryotes. Nucleic Acids Res.  

Walsh, L. A., & Quail, D. F. (2023). Decoding the tumor microenvironment with spatial technologies. Nat Immunol, 24(12), 1982-1993.  

Textor, J., Buytenhuijs, F., Rogers, D., Gauthier, E. M., Sultan, S., Wortel, I. M. N., Kalies, K., Fahnrich, A., Pagel, R., Melichar, H. J., Westermann, J., & Mandl, J. N. (2023). Machine learning analysis of the T cell receptor repertoire identifies sequence features of self-reactivity. Cell Syst.  

Taifour, T., Attalla, S. S., Zuo, D., Gu, Y., Sanguin-Gendreau, V., Proud, H., Solymoss, E., Bui, T., Kuasne, H., Papavasiliou, V., Lee, C. G., Kamle, S., Siegel, P. M., Elias, J. A., Park, M., & Muller, W. J. (2023). The tumor-derived cytokine Chi3l1 induces neutrophil extracellular traps that promote T cell exclusion in triple-negative breast cancer. Immunity.  

Tankel, J., Meng, A., Gold, M., Mueller, C., Spicer, J., Cools-Lartigue, J., Ferri, L., & Najmeh, S. (2023). Transabdominal Management of Epiphrenic Diverticula in the Setting of Achalasia: A Single-center Review. Surg Laparosc Endosc Percutan Tech.  

Sharma, V., Oliveira, M. M., Sood, R., Khlaifia, A., Lou, D., Hooshmandi, M., Hung, T. Y., Mahmood, N., Reeves, M., Ho-Tieng, D., Cohen, N., Cheng, P. C., Rahim, M. M. A., Prager-Khoutorsky, M., Kaufman, R. J., Rosenblum, K., Lacaille, J. C., Khoutorsky, A., Klann, E., & Sonenberg, N. (2023). mRNA translation in astrocytes controls hippocampal long-term synaptic plasticity and memory. Proc Natl Acad Sci U S A, 120(49), e2308671120.   

Xia, H., Dufour, C. R., Medkour, Y., Scholtes, C., Chen, Y., Guluzian, C., B'Chir, W., & Giguere, V. (2023). Hepatocyte FBXW7-dependent activity of nutrient-sensing nuclear receptors controls systemic energy homeostasis and NASH progression in male mice. Nat Commun, 14(1), 6982.  

Wong, C., Tavares-Ferreira, D., Thorn Perez, C., Sharif, B., Uttam, S., Amiri, M., Lister, K. C., Hooshmandi, M., Nguyen, V., Seguela, P., Sonenberg, N., Price, T. J., Gkogkas, C. G., & Khoutorsky, A. (2023). 4E-BP1-dependent translation in nociceptors controls mechanical hypersensitivity via TRIM32/type I interferon signaling. Sci Adv, 9(44), eadh9603.  

Cagnetta, R., Flanagan, J. G., & Sonenberg, N. (2023). Control of Selective mRNA Translation in Neuronal Subcellular Compartments in Health and Disease. J Neurosci, 43(44), 7247-7263.  

Sepesi, B., Mehran, R., Spicer, J., & Cascone, T. (2023). Neostar Trial and The Current Status of Neoadjuvant Therapy in Non-Small Cell Lung Cancer. J Thorac Cardiovasc Surg.  

Cascone, T., Kar, G., Spicer, J. D., Garcia-Campelo, R., Weder, W., Daniel, D. B., Spigel, D. R., Hussein, M., Mazieres, J., Oliveira, J., Yau, E. H., Spira, A. I., Anagnostou, V., Mager, R., Hamid, O., Cheng, L. Y., Zheng, Y., Blando, J., Tan, T. H., Surace, M., Rodriguez-Canales, J., Gopalakrishnan, V., Sellman, B. R., Grenga, I., Soo-Hoo, Y., Kumar, R., McGrath, L., & Forde, P. M. (2023). Neoadjuvant Durvalumab Alone or Combined with Novel Immuno-Oncology Agents in Resectable Lung Cancer: The Phase II NeoCOAST Platform Trial. Cancer Discov, 13(11), 2394-2411.  
 

Pervin, J., Asad, M., Cao, S., Jang, G. H., Feizi, N., Haibe-Kains, B., Karasinska, J. M., O'Kane, G. M., Gallinger, S., Schaeffer, D. F., Renouf, D. J., Zogopoulos, G., & Bathe, O. F. (2023). Clinically impactful metabolic subtypes of pancreatic ductal adenocarcinoma (PDAC). Front Genet, 14, 1282824.  

Krochmalnek, E., Accogli, A., St-Onge, J., Addour-Boudrahem, N., Prakash, G., Kim, S. H., Brunette-Clement, T., Alhajaj, G., Mougharbel, L., Bruneau, E., Myers, K. A., Dubeau, F., Karamchandani, J., Farmer, J. P., Atkinson, J., Hall, J., Chantal Poulin, C., Rosenblatt, B., Lafond-Lapalme, J., Weil, A., Fallet-Bianco, C., Albrecht, S., Sonenberg, N., Riviere, J. B., Dudley, R. W., & Srour, M. (2023). mTOR Pathway Somatic Pathogenic Variants in Focal Malformations of Cortical Development: Novel Variants, Topographic Mapping, and Clinical Outcomes. Neurol Genet, 9(6), e200103.

Aksoylu, I. S., Martin, P., Robert, F., Szkop, K. J., Redmond, N. E., Bhattacharyya, S., Wang, J., Chen, S., Beauchamp, R. L., Nobeli, I., Pelletier, J., Larsson, O., & Ramesh, V. (2023). Translatome analysis of tuberous sclerosis complex 1 patient-derived neural progenitor cells reveals rapamycin-dependent and independent alterations. Mol Autism, 14(1), 39.  

Wiede, F., Shields, B. J., Kyparissoudis, S., van Vliet, C., Galic, S., Tremblay, M. L., Russell, S. M., Godfrey, D. I., & Tiganis, T. (2023). T cell protein tyrosine phosphatase attenuates T cell signaling to maintain tolerance in mice. J Clin Invest, 133(20).

Farncombe, K. M., Wong, D., Norman, M. L., Oldfield, L. E., Sobotka, J. A., Basik, M., Bombard, Y., Carile, V., Dawson, L., Foulkes, W. D., Malkin, D., Karsan, A., Parkin, P., Penney, L. S., Pollett, A., Schrader, K. A., Pugh, T. J., Kim, R. H., & consortium, C. (2023). Current and new frontiers in hereditary cancer surveillance: Opportunities for liquid biopsy. Am J Hum Genet, 110(10), 1616-1627.
 
Tankel, J., & Ferri, L. (2023). Chemotherapy is the preferred neoadjuvant treatment of oesophageal adenocarcinoma. Br J Surg.
 
Xia, H., Scholtes, C., Dufour, C. R., Guluzian, C., & Giguere, V. (2023). ERRalpha fosters running endurance by driving myofiber aerobic transformation and fuel efficiency. Mol Metab, 101814.  
 
Audet-Delage, Y., St-Louis, C., Minarrieta, L., McGuirk, S., Kurreal, I., Annis, M. G., Mer, A. S., Siegel, P. M., & St-Pierre, J. (2023). Spatiotemporal modeling of chemoresistance evolution in breast tumors uncovers dependencies on SLC38A7 and SLC46A1. Cell Rep, 42(10), 113191.
 
Mandl, J. N., & Melichar, H. J. (2023). Revealing the identity of regulatory T-cell-suppressed self-reactive CD4(+) T cells. Cell Mol Immunol, 20(10), 1093-1094.  
 

Nevo, Y., & Ferri, L. (2023). Current management of gastric adenocarcinoma: a narrative review. J Gastrointest Oncol, 14(4), 1933-1948.  

Mony, S., Hu, B., Joseph, A., Aihara, H., Ferri, L., Bhatt, A., Mehta, A., Ting, B., Chen, A., Kalra, A., Farha, J., Onimaru, M., Wang, A., He, L., Luo, Q., Inoue, H., & Ngamruengphong, S. (2023). Clinical Outcomes of Endoscopic Submucosal Dissection for Superficial Esophageal Neoplasia in Close Proximity to Esophageal Varices: A Multicenter International Experience. Endoscopy.  
 
Ford, M. J., Harwalkar, K., Kazemdarvish, H., Yamanaka, N., & Yamanaka, Y. (2023). CD133/Prom1 marks proximal mouse oviduct epithelial progenitors and adult epithelial cells with a low generative capacity. Biol Open.
 
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